AGAnchorGPU

H200 SXM vs MI300X

H200 SXM vs MI300X: specs and rental cost

Compare memory, node configurations, and fixed weekly and monthly cost before choosing between NVIDIA H200 SXM and AMD Instinct MI300X.

Decision summary

MI300X provides 51 GB more VRAM per card. MI300X costs $560 less per 30-day term . Choose based on whether memory headroom or lower fixed cost is the binding constraint.

NVIDIA

H200 SXM

LLM inference · fine-tuning

$1,832/ 30 days
View GPU
VS
AMD

MI300X

large models · ROCm workloads

$1,272/ 30 days
View GPU
SpecificationH200 SXMMI300X
ArchitectureHopperCDNA 3
VRAM141 GB HBM3e192 GB HBM3
Host resources / card24 vCPU · 192 GB RAM28 vCPU · 256 GB RAM
Local NVMe / card3.84 TB3.84 TB
7-day price / card$512$360
30-day price / card$1,832$1,272
4-GPU node / 30 days$6,742$4,681
Catalog quantity265 cards430 cards

Workload decision · updated 2026-09-04

H200 SXM vs MI300X: memory headroom or CUDA continuity?

H200 offers 141 GB on the Hopper CUDA platform; MI300X offers 192 GB on AMD’s ROCm platform. More memory can simplify the model layout, while retaining an already-qualified software stack can reduce migration work.

01

Choose H200 SXM when…

Choose H200 when the application depends on CUDA-only extensions, Hopper-validated containers or NVIDIA libraries that have not been qualified on ROCm. The larger memory capacity relative to an 80 GB card may reduce the need for sharding.

02

Choose MI300X when…

Choose MI300X when 192 GB can avoid a multi-GPU split and the complete workload has passed testing on ROCm. Validate the serving or training backend, custom operations, attention kernels and quantization format, not just a successful PyTorch import.

Manufacturer specificationH200 SXMMI300X
ArchitectureNVIDIA HopperAMD CDNA 3
Memory141 GB HBM3e192 GB HBM3
Published memory bandwidth4.8 TB/s5.3 TB/s peak theoretical
Primary software stackCUDAROCm
Reference accelerator fabricNVLink in HGX systemsInfinity Fabric in MI300X platforms

Published accelerator specifications, not a measurement of AnchorGPU infrastructure. Host topology and delivered fabric must be confirmed separately.

What to verify in a pilot

  • Inventory custom CUDA extensions, attention kernels, quantization kernels and collective operations.
  • Validate model loading, a representative request or step, numerical output and checkpoint restore.
  • Measure the KV cache or training state alongside model weights; capacity is not just parameter count.
  • Do not interpret memory bandwidth specifications as measured tokens per second or training speed.

Bottom line. Prefer H200 for CUDA-dependent continuity. Evaluate MI300X when a validated ROCm path and larger single-accelerator memory reduce your application’s complexity.

Catalog cost difference: $152 per 7 days and $560 per 30 days. Prices are read from the same catalog as the configurator.

Sources & method

Manufacturer specifications inform the comparison. Recommendations are workload-dependent; no AnchorGPU performance benchmark is claimed.

NVIDIA H200 specificationsAMD MI300X specificationsPyTorch on ROCm