AGAnchorGPU

MI300X vs RTX 5090

MI300X vs RTX 5090: specs and rental cost

Compare memory, node configurations, and fixed weekly and monthly cost before choosing between AMD Instinct MI300X and NVIDIA RTX 5090.

Decision summary

MI300X provides 160 GB more VRAM per card. RTX 5090 costs $840 less per 30-day term . Choose based on whether memory headroom or lower fixed cost is the binding constraint.

AMD

MI300X

large models · ROCm workloads

$1,272/ 30 days
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VS
NVIDIA

RTX 5090

image generation · local inference

$432/ 30 days
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SpecificationMI300XRTX 5090
ArchitectureCDNA 3Blackwell
VRAM192 GB HBM332 GB GDDR7
Host resources / card28 vCPU · 256 GB RAM16 vCPU · 128 GB RAM
Local NVMe / card3.84 TB2 TB
7-day price / card$360$124
30-day price / card$1,272$432
4-GPU node / 30 days$4,681$1,590
Catalog quantity430 cards595 cards