AGAnchorGPU

MI300X vs L40S

MI300X vs L40S: specs and rental cost

Compare memory, node configurations, and fixed weekly and monthly cost before choosing between AMD Instinct MI300X and NVIDIA L40S.

Decision summary

MI300X provides 144 GB more VRAM per card. L40S costs $856 less per 30-day term . Choose based on whether memory headroom or lower fixed cost is the binding constraint.

AMD

MI300X

large models · ROCm workloads

$1,272/ 30 days
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VS
NVIDIA

L40S

video · inference

$416/ 30 days
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SpecificationMI300XL40S
ArchitectureCDNA 3Ada
VRAM192 GB HBM348 GB GDDR6 ECC
Host resources / card28 vCPU · 256 GB RAM16 vCPU · 128 GB RAM
Local NVMe / card3.84 TB2 TB
7-day price / card$360$118
30-day price / card$1,272$416
4-GPU node / 30 days$4,681$1,531
Catalog quantity430 cards430 cards